OUR PAPERS

Authors from Queen's University are in bold.

2025

Class IV plant U-box proteins function redundantly to optimize protein accumulation of receptor-like cytoplasmic kinase BIK1. 
  • Authors: Dou R, Miguel VN, Grubb LE, Rana M, Saltzman B, Monaghan J.
  • Read the preprint on BioRxiv.


Conservation of an immune homeostasis module in land plants. 
  • Authors: Dou R, El Mahboubi K, Tanney CAS, Chu J, Bredow M, Rodrigues Gallo MC, Lauressergues D, Keller J, Miguel VN, DeFalco TA, Uhrig RG, Zipfel C, Delaux PM, Monaghan J.
  • Read the preprint on BioRxiv


Catalytically inactive subgroup VIII receptor-like cytoplasmic kinases regulate the immune-triggered oxidative burst in Arabidopsis thaliana. 
  • Authors: Goncalves Dias M, Dharmasena T, Gonzalez-Ferrer C, Maika JE, Miguel VN, Dou R, Rodrigues Gallo MC, Bredow M, Siegel KR, Uhrig RG, Simon R, Monaghan J. 
  • Read the paper in Journal of Experimental Botany or on BioRxiv 

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A quick guide to the calcium-dependent protein kinase family in Brassica napus. 
  • Authors: Miguel VN, Monaghan J. 
  • Read the paper in Genome.

2024
Arabidopsis thaliana protein NSL1 interacts with Pseudomonas syringae pv. tomato DC3000 effector HopM1 in a yeast 2-hybrid assay.

Subfamily C7 Raf-like kinases MRK1, RAF26, and RAF39 regulate immune homeostasis and stomatal opening in Arabidopsis thaliana.
  • Authors: Goncalves Dias M, Doss B, Rawat A, Siegel KR, Mahathanthrige T, Sklenar J, Derbyshire P, Dharmesana T, Cameron E, Zipfel C, Menke FLH, Monaghan J. 
  • Read the paper in New Phytologist or on BioRxiv


A cyclic lipopeptide from Fusarium graminearum targets plant membranes to promote virulence.
  • Authors: Brauer E, Bosnich W, Holy K, Thapa I, Krishnan S, Syed M,  Bredow M, Sproule M, Power M,  Johnston A, Cloutier M, Haribabu N, Khan IUH, Diallo J-S, Monaghan J, Chabot D,  Overy DP, Subramaniam R, Piñeros M,  Blackwell B, Harris LJ.
  • Read the paper in Cell Reports or on SSRN.  
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Editorial Overview: Biotic Interactions Edition

2023
Substrate profiling of the Arabidopsis calcium-dependent protein kinase AtCPK4 and its Ricinus communis ortholog RcCDPK1.
  • Authors: Kilburn R, Fedosejevs ET, Mehta D, Soleimani F, Ghahremani M, Monaghan J, Thelen JJ, Uhrig RG, Snedden WA, Plaxton WC. 
  • Read the paper in Plant Science.


Arabidopsis translation initiation factor binding protein CBE1 negatively regulates accumulation of the NADPH oxidase respiratory burst oxidase homolog D

Running a Research Group in the Next Generation: Combining sustainable and reproducible research with values-driven leadership.

2022
Cross-kingdom regulation of calcium- and/or calmodulin-regulated protein kinases by phospho-switches that relieve autoinhibition.
Activation and turnover of the immune signaling kinase BIK1: A fine balance. 
Evolution and functions of plant U-box proteins: From protein quality control to signaling

2021
Phosphorylation-dependent subfunctionalization of the calcium-dependent protein kinase CPK28.
Truncated variants of calcium-dependent protein kinases: A conserved mechanism?
Differential regulation of the calcium-dependent protein kinase CPK28 by site-specific modification. 
Receptor-like cytoplasmic kinase MAZZA mediates developmental processes with CLAVATA1-family receptors in Arabidopsis. 
  • Authors: Schulz P, Schlegel J, Gonzalez-Ferrer C, Becher S, Gustavo Pinto K, Monaghan J, Simon R.
  • Read the paper in Journal of Experimental Botany. 
  • Check out this Insight Article about this work: 

A novel allele of the Arabidopsis thaliana MACPF protein CAD1 results in deregulated immune signaling. 
  • Authors: Holmes DR, Bredow M, Thor K, Pascetta S, Sementchoukova I, Siegel KR, Zipfel C, Monaghan J.
  • Read the paper in Genetics ​​or BioRxiv. 

Proteobacteria contain diverse flg22 peptides that elicit varying responses in Arabidopsis thaliana. 
Large-scale identification of ubiquitination sites on membrane-associated proteins in Arabidopsis thaliana. 
  • Authors: Grubb LE, Derbyshire P, Dunning KE, Zipfel C, Menke FLH, Monaghan J.
  • Read the paper in Plant Physiology or BioRxiv. 

2019
Pattern-triggered oxidative burst and seedling growth inhibition assays in Arabidopsis thaliana. 
Modulation of plant innate immune signaling by small peptides.
Regulation of plant immune signaling by calcium-dependent protein kinases.
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2018
The jasmonate receptor COI1 is required for AtPep1-induced immune responses in Arabidopsis thaliana.
A regulatory module controlling homeostasis of a plant immune kinase.
  • ​​Authors: Wang J, Grubb LE, Wang J, Liang X, Li L, Gao C, Ma M, Feng F, Li M, Li L, Zhang X, Yu F, Xie Q, Chen S, Zipfel C, Monaghan J, Zhou JM.
  • Read the paper in Molecular Cell.
  • Check out these Spotlight articles about this work:
    • ​Monaghan J. (2018) Conserved degradation of orthologous RLCKs maintains immune homeostasis. Trends in Plant Science, 23: 555-558.
    • ​Xu et al., (2020) Differential Ubiquitination of BIK1 Fine-Tunes Plant Immunity. Trends in Plant Science, 26: 1-2. 
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2017
Autophosphorylation-based calcium (Ca2+) sensitivity priming and Ca2+/Calmodulin inhibition of Arabidopsis thaliana Ca2+-dependent protein kinase 28 (CPK28). ​
  • Authors: Bender K, Blackburn RK, Monaghan J, Derbyshire P, Menke FLH, Zipfel C, Goshe MB, Zielinski RE, Huber SC.
  • Read the paper in Journal of Biological Chemistry.

The receptor kinase FER is a RALF-regulated scaffold controlling plant immune signaling.
  • ​​Authors: Stegmann M, Monaghan J,  Smakowska-Luzan E, Rovenich H, Lehner A, Holton N, Belkhadir Y, Zipfel C.
  • Read the paper in Science.
  • Check out this article about the study in the Queen's Gazette. 
To read Jacqueline's PhD and Postdoctoral work, please visit:
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