This week our group spent two days away from the lab at Queen's University Biological Station. We worked in the main lodge by a wood-burning stove for hours, going over the direction of everyone's projects and thinking about 'the bigger picture'. Prior to the retreat, everyone shared summaries of their results, paper/thesis outlines, and a list of readings. Although we have weekly lab meetings, this intensive and cozy retreat allowed our hive mind to thrive and everyone left eager to get back to their benches and test hypotheses. 

After a very successful thesis defence yesterday, Lauren is now the first MSc student to graduate from the Monaghan Lab. What a milestone! I am so proud of all of Lauren's many achievements and her now almost-complete thesis 'Analysis of E3 ligases and identification of ubiquitination sites regulating turnover of the plant immune signalling kinase BIK1'.

Lauren joined the lab in May 2016 as a summer student with an NSERC Undergraduate Summer Research Award, prior to starting as a MSc student that September. Her graduate work was supported by an NSERC Canada Graduate Scholarship and Michael Smith Foreign Study Supplement in her first year and an Ontario Graduate Scholarship in her second year.  Lauren graduates as co-author of two publications, with another in the pipeline. Her work on identifying in vivo BIK1 ubiquitination sites, which she did during a 4-month stay abroad under the guidance of Frank Menke at the Sainsbury Lab, has advanced our research into BIK1 turnover and set the groundwork for additional thesis projects. In addition to working hard at the bench, Lauren also excelled in her coursework and organized the Molecular, Cell & Integrative Biology seminar series for our department for the last 2 years.  

Lauren was accepted into the highly-competitive International PhD Rotation Programme at the John Innes Centre/Earlham Institute/Sainsbury Lab, in Norwich UK, and starts next week! 

 Congratulations Lauren, and best wishes during your PhD. The lab won't be the same without you! 

​Our short open-access paper ‘The jasmonate receptor COI1 is required for AtPep1-induced immune responses in Arabidopsis thaliana’ is now published in BMC Research Notes. This work stemmed from a curious observation made by first author Danalyn Holmes during her Honours thesis project. While performing other experiments that required use of the jasmonate receptor mutant coi1-16 as a control genotype, she was surprised to find that coi1-16 was specifically compromised in AtPep1-, but not flg22- or elf18-, triggered immune responses. Dependence of AtPep1-mediated signaling on jasmonate perception has been observed previously; her observations build on and corroborate these previous findings.

Danalyn had already moved to Germany to start her PhD when the article was accepted, so second author Lauren Grubb popped the champagne and we celebrated at the Grad Club via Skype. Congrats!