Arabidopsis (Arabidopsis thaliana) AtBIK1 and rice (Oryza sativa) OsRLCK176 are orthologous receptor-like cytoplasmic kinases involved in plant immune signaling. In this Trends in Plant Science Spotlight article, I review several recent studies suggesting that proteasomal turnover of these kinases is regulated by orthologous group IV Ca2+-dependent protein kinases AtCPK28 and OsCPK4, revealing conserved interplay between phosphorylation and ubiquitination in immune homeostasis.  

Read the original articles: 

• Furlan et al., 2017. Changes in PUB22 ubiquitination modes triggered by MPK3 dampen the immune response. Plant Cell. 
• Monaghan et al., 2014. The calcium dependent protein kinase CPK28 buffers plant immunity and regulates BIK1 turnover. Cell Host Microbe.
• Wang et al., 2017. The kinase OsCPK4 regulates a buffering mechanism that fine-tunes innate immunity. Plant Physiology.
• Wang et al., 2018. A regulatory module controlling homeostasis of a plant immune kinase. Molecular Cell.